Cobalt Manganese Oxide Nano Catalysts as a Recyclable Catalyst for the Synthesis of 3,4- Dihydropyrimidin-2(1H)-ones-thiones
In the recent years, multicomponent condensation reactions was discovered to be a powerful method for the synthesis of organic compounds, since the products have been produced in a single step, and the diversity can be achieved by simply varying each component, As an example, The 3,4-dihydropyrimidin- 2(1H)-ones-thiones (DHPMs) are known to exhibit a wide range of biological activities such as antitumour, antiviral, anti-inflammatory actions and antibacterial. Therefore, this heterocyclic nucleus has gained a great importance and several modified procedures of the original Biginelli protocol.
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Synthesis and Reactivity in Inorganic, Metal-Organic, and Nano-Metal Chemistry (2015) 45, 271–276